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Mutation Information

Literature Information

PubMed PMID	30824746
Published Year	2019
Journal	Scientific reports
Title	A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation.
Author	Ruiz AP,Ajasin DO,Ramasamy S,DesMarais V,Eugenin EA,Prasad VR
Evidence	Here, we report that in the globally dominant HIV-1 clade C, Tat displays a naturally occurring polymorphism, R57S, in its basic domain, which mediates cellular uptake.

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Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)