|
Mutation Information
|
Mutation Site
|
R52W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
17958917
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
|
Journal
|
Virology journal |
|
Title
|
Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort. |
|
Author
|
Sivakumaran H,Wang B,Gill MJ,Beckholdt B,Saksena NK,Harrich D |
|
Evidence
|
The general attenuation seen in all of recipient C's Tat clones is most likely due to two mutations, Y47H and R52W, located in the highly conserved core and basic domains (respectively) of Tat.
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HIV Mutation Detail Information