|
Mutation Information
|
Mutation Site
|
R515A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
|
Combined Mutation
|
env.R515A+ca.Q155N;env.R515A+ca.Y164A |
Literature Information
|
PubMed PMID
|
21529874
|
|
Published Year
|
2011 |
|
Journal
|
Virology |
|
Title
|
Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy. |
|
Author
|
Joshi A,Garg H,Ablan S,Freed EO,Nagashima K,Manjunath N,Shankar P |
|
Evidence
|
Both the Envelope mutants tested, V513E and R515A, were equally effective and a combination of Gag and Envelope DN genes significantly enhanced potency.
|
|
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HIV Mutation Detail Information