HIV Mutation Detail Information

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Mutation Information
Mutation Site R503W
Mutation Type Amino acid level
Gene/Protein/Region Type Env
Literature Information
PubMed PMID 30566493
Published Year 2018
Journal PloS one
Title Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant.
Author Beltran-Pavez C,Ferreira CB,Merino-Mansilla A,Fabra-Garcia A,Casadella M,Noguera-Julian M,Paredes R,Olvera A,Haro I,Brander C,Garcia F,Gatell JM,Yuste E,Sanchez-Merino V
Evidence Only 3 out of the 37 amino acid replacements observed with a frequency above 5% (D138Y, R503W and K574M) have an acceptability value below 3, supporting the notion of poorly accepted mutations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation