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Mutation Information
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Mutation Site
|
R456W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
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Country
|
South Africa |
Literature Information
|
PubMed PMID
|
29950423
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Journal of virology |
|
Title
|
HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes. |
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Author
|
Ditse Z,Muenchhoff M,Adland E,Jooste P,Goulder P,Moore PL,Morris L |
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Evidence
|
In addition to binding assays, neutralization assays were performed using viruses with mutations in the CD4bs epitope (N276A, N279A, and R456W).
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HIV Mutation Detail Information