|
Mutation Information
|
Mutation Site
|
R42A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Rev |
|
Viral Reference
|
K03455.1
|
Literature Information
|
PubMed PMID
|
17176473
|
|
Published Year
|
2006 |
|
Journal
|
Retrovirology |
|
Title
|
PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA. |
|
Author
|
Invernizzi CF,Xie B,Richard S,Wainberg MA |
|
Evidence
|
The mutant proteins R41A and R42A still produced bands with intensities of 90% and 68% of wild-type Rev, respectively, showing that these residues are not primary substrates of PRMT6.
|
|
|
HIV Mutation Detail Information