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Mutation Information
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Mutation Site
|
R393H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BXLF1 |
Literature Information
|
PubMed PMID
|
14705959
|
|
Published Year
|
2004 |
|
Journal
|
The Biochemical journal |
|
Title
|
Identification and characterization of the conserved nucleoside-binding sites in the Epstein-Barr virus thymidine kinase. |
|
Author
|
Wu CC,Chen MC,Chang YR,Hsu TY,Chen JY |
|
Evidence
|
For site 3, only mutants D392E (Asp392-->Glu) and R393H retain activity, indicating that a negative charge is important for Asp392 and a positive charge is required for Arg393.
|
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EBV Mutation Detail Information