|
Mutation Information
|
Mutation Site
|
R31V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vpu |
Literature Information
|
PubMed PMID
|
17910056
|
|
Published Year
|
2008 |
|
Journal
|
Proteins |
|
Title
|
Biophysical characterization of Vpu from HIV-1 suggests a channel-pore dualism. |
|
Author
|
Mehnert T,Routh A,Judge PJ,Lam YH,Fischer D,Watts A,Fischer WB |
|
Evidence
|
Peptides corresponding to the TM domain of Vpu (Vpu1-32) and mutant peptides (Vpu1-32-W23L, Vpu1-32-R31V, Vpu1-32-S24L) have been synthesized and reconstituted into artificial lipid bilayers.
|
|
|
HIV Mutation Detail Information