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Mutation Information
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Mutation Site
|
R302T |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E2 |
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Genotype/Subtype
|
HPV16 |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
33324377
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2020 |
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Journal
|
Frontiers in microbiology |
|
Title
|
High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer. |
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Author
|
Hirose Y,Yamaguchi-Naka M,Onuki M,Tenjimbayashi Y,Tasaka N,Satoh T,Tanaka K,Iwata T,Sekizawa A,Matsumoto K,Kukimoto I |
|
Evidence
|
Among the high-level variations found in ICC, six were located in the E1/E2 genes, and all of them were non-synonymous substitutions (Q142K, M207I, and L262V for E1; D153Y, R302T, and T357A for E2).
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HPV Mutation Detail Information