|
Mutation Information
|
Mutation Site
|
R263K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
CRF02_AG |
|
Relevant Drug
|
INSTIs |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
33892628
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Interaction analysis of statistically enriched mutations identified in Cameroon recombinant subtype CRF02_AG that can influence the development of Dolutegravir drug resistance mutations. |
|
Author
|
Mikasi SG,Isaacs D,Chitongo R,Ikomey GM,Jacobs GB,Cloete R |
|
Evidence
|
RESULTS: We observed 12.8% (37/287) sequences to contain RAMs, with only 1.0% (3/287) of the sequences having major INSTI RAMs: T66A, Q148H, R263K and N155H.
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|
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HIV Mutation Detail Information