Mutation Information
Mutation Site
|
R263A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
33712691
|
Published Year
|
2021 |
Journal
|
Communications biology |
Title
|
Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. |
Author
|
Pandey KK,Bera S,Shi K,Rau MJ,Oleru AV,Fitzpatrick JAJ,Engelman AN,Aihara H,Grandgenett DP |
Evidence
|
IN mutant viruses R263A and R263K, which altered conserved RSV IN residue Arg263, supported ~20% and 50% of the level of wt 1-323 infection, respectively (Fig. 5c).
|
|
|