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EBV Mutation Detail Information

> R256E Search Result


Mutation Information
Mutation Site R256E
Mutation Type Amino acid level
Gene/Protein/Region Type BMRF1
Literature Information
PubMed PMID 20926567
Published Year 2010
Journal Journal of virology
Title Tetrameric ring formation of Epstein-Barr virus polymerase processivity factor is crucial for viral replication.
Author Nakayama S,Murata T,Yasui Y,Murayama K,Isomura H,Kanda T,Tsurumi T
Evidence The R256E virus, which has a severely impaired capacity for DNA binding and polymerase processivity, failed to form replication compartments, resulting in interference of viral replication, while the C95E mutation, which impairs head-to-head contact in vitro, unexpectedly hardly affected the viral replication.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation