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Mutation Information
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Mutation Site
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R23A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vif |
Literature Information
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PubMed PMID
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24422669
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Published Year
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2014 |
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Journal
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Retrovirology |
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Title
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HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3. |
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Author
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Evans SL,Schön A,Gao Q,Han X,Zhou X,Freire E,Yu XF |
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Evidence
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In agreement with our prior observation that His28 was unimportant for Vif-Cul5 formation, the Vif-H28A mutant along with Vif-R23A were both capable of inducing A3G and A3F degradation similarly to wild-type Vif (Figure 2A, A,2B).2B).
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HIV Mutation Detail Information