Mutation Information
Mutation Site
|
R190S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Combined Mutation
|
tax.R190S+tax.K189A |
Literature Information
PubMed PMID
|
14645559
|
Published Year
|
2003 |
Journal
|
Journal of virology |
Title
|
The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization. |
Author
|
Basbous J,Bazarbachi A,Granier C,Devaux C,Mesnard JM |
Evidence
|
Moreover, the Tax mutants M22 (T130A and L131S) and M29 (K189A and R190S), with amino acid substitutions located in DD1 and DD2, respectively, were found to be impaired in Tax self-association.
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