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Mutation Information
|
Mutation Site
|
R18S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AF286594.1
|
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
20119580
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Journal of Korean medical science |
|
Title
|
Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations. |
|
Author
|
Kim JH,Jung YK,Joo MK,Kim JH,Yim HJ,Park JJ,Kim JS,Bak YT,Yeon JE,Byun KS |
|
Evidence
|
In Group C, there was one case of each of the following mutations: N4K, T7A, H9Q, R16P, R16G, V17P, V17A, R18S, G19S, L20Q, P54Q, nucleotide 418-423 deletion (a.a. 21-22), 419 deletion (a.a. 21), and 425 deletion (a.a. 30).
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HBV Mutation Detail Information