|
Mutation Information
|
Mutation Site
|
R18A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
|
Viral Reference
|
K03455.1
|
Literature Information
|
PubMed PMID
|
30862755
|
|
Published Year
|
2019 |
|
Journal
|
mBio |
|
Title
|
Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket. |
|
Author
|
Craveur P,Gres AT,Kirby KA,Liu D,Hammond JA,Deng Y,Forli S,Goodsell DS,Williamson JR,Sarafianos SG,Olson AJ |
|
Evidence
|
Furthermore, R18A and R18A/N21A have been previously shown to impact the morphology of the in vitro CA assemblies by shifting the observed phenotypes to spheres, cones, spirals, and short capped cylinders.
|
|
|
HIV Mutation Detail Information