HIV Mutation Detail Information

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Mutation Information

Mutation Site	R189S
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Genotype/Subtype	CRF01_AE
Viral Reference	AF038399.1
Country	Thailand

Literature Information

PubMed PMID	31010245
Disease	HIV infection/AIDS
Published Year	2019
Journal	Cells
Title	Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.
Author	Trinh HV,Gohain N,Pham PT,Hamlin C,Song H,Sanders-Buell E,Bose M,Eller LA,Jain S,Uritskiy G,Rao VB,Tovanabutra S,Michael NL,Robb ML,Joyce MG,Rao M
Evidence	However, antibody responses to peptide 3b, which included all of the SGA-observed variants in segment 3, or peptide 3c, which included only 1 of the segment 3 mutations (Arg189eSer) resulted in approximately a 3-fold lower antibody response compared to the corresponding T/F 3a peptide (Figure 4b).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation