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Mutation Information
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Mutation Site
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R169L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
S |
Literature Information
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PubMed PMID
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29604477
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Published Year
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2018 |
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Journal
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Virology |
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Title
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Impact of immune escape mutations and N-linked glycosylation on the secretion of hepatitis B virus virions and subviral particles: Role of the small envelope protein. |
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Author
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Bi X,Tong S |
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Evidence
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By simultaneous detection of HBsAg in cell lysate and culture supernatant using this ELISA kit, we found that HBsAg secretion (as defined by ratio of cextracellular HBsAg/intracellular HBsAg) was severely impaired by the C138Y, R169L, R169P, and C149R mutations (Fig. 7C).
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HBV Mutation Detail Information