HIV Mutation Detail Information

> R15S Search Result

Mutation Information

Mutation Site	R15S
Mutation Type	Amino acid level
Gene/Protein/Region Type	Vif
Viral Reference	K03455.1

Literature Information

PubMed PMID	31665623
Published Year	2019
Journal	Cell reports
Title	HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators.
Author	Salamango DJ,Ikeda T,Moghadasi SA,Wang J,McCann JL,Serebrenik AA,Ebrahimi D,Jarvis MC,Brown WL,Harris RS
Evidence	For example, R15S, K22T, I31F, R33G, and N48T were predicted to have compromised ability to degrade EGFP-PPP2R5A, and indeed, these substitutions failed to reduce EGFP-PPP2R5A levels compared with wild-type Vif (Figure 1E).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation