Mutation Information
Mutation Site
|
R15E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vif |
Literature Information
PubMed PMID
|
32471198
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
Structural Insights into APOBEC3-Mediated Lentiviral Restriction. |
Author
|
Delviks-Frankenberry KA,Desimmie BA,Pathak VK |
Evidence
|
As predicted from previous studies indicating the importance of the 14DRMR17 motif in Vif, the Vif mutants R15D or R15E failed to induce degradation of WT A3F or rescue infectivity in single replication cycle assays.
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