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HIV Mutation Detail Information

> R15D Search Result


Mutation Information
Mutation Site R15D
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Literature Information
PubMed PMID 32471198
Published Year 2020
Journal Viruses
Title Structural Insights into APOBEC3-Mediated Lentiviral Restriction.
Author Delviks-Frankenberry KA,Desimmie BA,Pathak VK
Evidence As predicted from previous studies indicating the importance of the 14DRMR17 motif in Vif, the Vif mutants R15D or R15E failed to induce degradation of WT A3F or rescue infectivity in single replication cycle assays.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation