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Mutation Information
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Mutation Site
|
R151T |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
|
Combined Mutation
|
e6.D32E+e6.R151T |
|
Amino acid_Mutation
|
C451A/T453C |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26192265
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
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Published Year
|
2016 |
|
Journal
|
Journal of medical virology |
|
Title
|
Distribution of human papilloma virus type 16 E6/E7 gene mutation in cervical precancer or cancer: A case control study in Guizhou Province, China. |
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Author
|
Yang Y,Ren J,Zhang Q |
|
Evidence
|
The detection rate at each site was listed as follows: D32E (DNA sequence T96A, similarly herein after), 40.7% (33/81); D32E + R5G (T96A + C13G + T15C), 4.9% (4/81); D32E + R151T (T96A + C451A T96A + T453C), 2.5% (2/81); L83V (C268G), 6.2% (5/81); V35M + D51N (G112A + G151A), 3.7% (3/81); and C87R (T259A), 4.9% (4/81).
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HPV Mutation Detail Information