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Mutation Information
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Mutation Site
|
R132A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
CA |
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Viral Reference
|
K02013.1
|
Literature Information
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PubMed PMID
|
24415937
|
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Published Year
|
2014 |
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Journal
|
PLoS pathogens |
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Title
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In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. |
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Author
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Henning MS,Dubose BN,Burse MJ,Aiken C,Yamashita M |
|
Evidence
|
We depleted endogenous CPSF6 and infected the cells either with CA mutants that become dependent on cell division (E45A, Q63A/Q67A, A92E, G94D, and Q219A) or those that are impaired for infection but maintain cell cycle independence for infection (P38A, E71A, E128A/R132A and R143A).
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HIV Mutation Detail Information