|
Mutation Information
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Mutation Site
|
R124G |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
12551970
|
|
Published Year
|
2003 |
|
Journal
|
Journal of virology |
|
Title
|
Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways. |
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Author
|
Le Roux LG,Moroianu J |
|
Evidence
|
Significantly, an E6(R124G) mutant had reduced nuclear import activity, and the E6 deletion mutant lacking (121)KKQR(124) was not imported into the nucleus.
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HPV Mutation Detail Information