HBV Mutation Detail Information

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Mutation Information

Mutation Site	R122K
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D
Country	Botswana

Literature Information

PubMed PMID	30382563
Disease	HBV-HIV coinfection
Published Year	2019
Journal	Virus genes
Title	Molecular characterization of hepatitis B virus in blood donors in Botswana.
Author	Choga WT,Anderson M,Zumbika E,Moyo S,Mbangiwa T,Phinius BB,Melamu P,Kayembe MK,Kasvosve I,Sebunya TK,Blackard JT,Essex M,Musonda RM,Gaseitsiwe S
Evidence	Twelve mutations including diagnostic escape mutations (sY100C, sR122K, sT123A, sC124R, sM133T), vaccine escape mutations (sT126N, sQ129R, sM133L, sF134V) and immunoglobulin therapy failure (sG119R, sG130N, sT140S) were exclusive to isolates obtained from HBV/HIV patients versus n = 4 including sP120L, sG130R, sY134H, and sD144A) (Fig 4) obtained from some isolates from blood donors.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation