HPV Mutation Detail Information

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Mutation Information

Mutation Site	R117K
Mutation Type	Amino acid level
Gene/Protein/Region Type	E1
Genotype/Subtype	HPV63
Viral Reference	X70828

Literature Information

PubMed PMID	28426749
Disease	HPV infection
Published Year	2017
Journal	PloS one
Title	Molecular characterization, tissue tropism, and genetic variability of the novel Mupapillomavirus type HPV204 and phylogenetically related types HPV1 and HPV63.
Author	Šterbenc A,Hošnjak L,Chouhy D,Bolatti EM,Oštrbenk A,Seme K,Kocjan BJ,Luzar B,Giri AA,Poljak M
Evidence	In addition, a consensus cyclin-binding motif (RXL) was identified at the N-termini of the E1 proteins of HPV204 and HPV1, whereas HPV63 harbors a R117K substitution in the first position of its cyclin-binding motif.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation