|
Mutation Information
|
Mutation Site
|
R10I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
10783118
|
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma
|
|
Published Year
|
2000 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Absence of antibody against human papillomavirus type 16 E6 and E7 in patients with cervical cancer is independent of sequence variations. |
|
Author
|
Nindl I,Zumbach K,Pawlita M,Teller K,Schneider A,Dürst M |
|
Evidence
|
Prototype (PT) and the following 5 variant antigens were used for RIPA: 350, 350G (L83V); 131/350, 131G (R10G)/350G (L83V); 335/350, 335T (H78Y)/350G (L83V); 345/350, 345G (Y81C)/350G (L83V); and Af2, 132T (R10I), 143G/145T (Q14D)/286A/289G/335T (H78Y)/403G.
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HPV Mutation Detail Information