HPV Mutation Detail Information

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Mutation Information

Mutation Site	R10G
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Amino acid_Mutation	A131G
Genotype/Subtype	HPV16
Country	India

Literature Information

PubMed PMID	19358280
Disease	Cervical carcinoma
Published Year	2009
Journal	International journal of cancer
Title	Molecular variants of HPV-16 associated with cervical cancer in Indian population.
Author	Pillai MR,Hariharan R,Babu JM,Lakshmi S,Chiplunkar SV,Patkar M,Tongaonkar H,Dinshaw K,Jayshree RS,Reddy BK,Siddiqui M,Roychoudury S,Saha B,Abraham P,Gnanamony M,Peedicayil A,Subhashini J,Ram TS,Dey B,Sharma C,Jain SK,Singh N
Evidence	An HPV‐16 E6 variant has been described with a nucleotide substitution A131G and a consequent amino acid change R10G that alters an HLA B7 peptide binding epitope.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation