HPV Mutation Detail Information

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Mutation Information
Mutation Site R10G
Mutation Type Amino acid level
Gene/Protein/Region Type E6
Amino acid_Mutation A131G
Genotype/Subtype HPV16
Literature Information
PubMed PMID 15006625
Disease Squamous-cell carcinoma; Head and neck carcinoma
Published Year 2004
Journal Oral oncology
Title Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas.
Author Hoffmann M,Lohrey C,Hunziker A,Kahn T,Schwarz E
Evidence The variant A131G in which the arginine at position 10 is replaced by glycine in the E6 protein (R10G) has also been detected in cervical cancer, albeit at a much lower frequency than the T350G variant.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation