HIV Mutation Detail Information

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Mutation Information
Mutation Site Q95K
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Combined Mutation in.Q95K+in.G163R
Relevant Drug INSTIs
Country Spain
Literature Information
PubMed PMID 32929472
Disease HIV infection/AIDS
Published Year 2020
Journal The Journal of antimicrobial chemotherapy
Title Primary resistance to integrase strand transfer inhibitors in Spain using ultrasensitive HIV-1 genotyping.
Author Casadellà M,Santos JR,Noguera-Julian M,Micán-Rivera R,Domingo P,Antela A,Portilla J,Sanz J,Montero-Alonso M,Navarro J,Masiá M,Valcarce-Pardeiro N,Ocampo A,Pérez-Martínez L,Pasquau J,Vivancos MJ,Imaz A,Carmona-Oyaga P,Muñoz-Medina L,Villar-García J,Barrufet P,Paredes R,INSTINCT Study Group.
Evidence Combinations of majority and minority INSTI mutations were found in three (2.1%) individuals analysed by NGS, including G163R (2.3%) + Q95K (2.3%), E138K (2.8%) + S230R (1.0%) and the previously described T97A (>99%) + R263K (1.9%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation