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Mutation Information
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Mutation Site
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Q74A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vif |
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Combined Mutation
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vif.Q74A+vif.W73A |
Literature Information
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PubMed PMID
|
28302150
|
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Published Year
|
2017 |
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Journal
|
Retrovirology |
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Title
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Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function. |
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Author
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Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK |
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Evidence
|
We generated CBFβ mutants W73A–Q74A, G75A–E76A, and Q77A–R78A and determined their ability to interact with Vif (Fig. 5b, c).
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HIV Mutation Detail Information