HIV Mutation Detail Information

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Mutation Information
Mutation Site Q74A
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Combined Mutation vif.Q74A+vif.W73A
Literature Information
PubMed PMID 28302150
Published Year 2017
Journal Retrovirology
Title Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function.
Author Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK
Evidence We generated CBFβ mutants W73A–Q74A, G75A–E76A, and Q77A–R78A and determined their ability to interact with Vif (Fig. 5b, c).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation