HIV Mutation Detail Information

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Mutation Information

Literature Information

PubMed PMID	22651890
Published Year	2012
Journal	Retrovirology
Title	Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.
Author	Kuo LS,Baugh LL,Denial SJ,Watkins RL,Liu M,Garcia JV,Foster JL
Evidence	Strikingly different from the Nef-Hck SH3 domain interaction is the failure of V74I to prevent Nef/activated PAK2 complex formation, and conversely, the elimination of Nef/activated PAK2 complex formation;by Q73R.

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Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)