HIV Mutation Detail Information

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Mutation Information

Mutation Site	Q61Y
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Viral Reference	AF038399.1
Country	Montreal and canda

Literature Information

PubMed PMID	32457241
Disease	HIV infection/AIDS
Published Year	2020
Journal	mBio
Title	The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site.
Author	Prévost J,Tolbert WD,Medjahed H,Sherburn RT,Madani N,Zoubchenok D,Gendron-Lepage G,Gaffney AE,Grenier MC,Kirk S,Vergara N,Han C,Mann BT,Chénine AL,Ahmed A,Chaiken I,Kirchhoff F,Hahn BH,Haim H,Abrams CF,Smith AB 3rd,Sodroski J,Pazgier M,Finzi A
Evidence	This was different from the results seen with respect to sCD4 neutralization, where viruses bearing LM changes without the Q61Y change were also sensitive to sCD4 neutralization (Fig. S1A and G).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation