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Mutation Information
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Mutation Site
|
Q58E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
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Relevant Drug
|
PIs |
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Country
|
china |
Literature Information
|
PubMed PMID
|
32576136
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
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Journal
|
BMC infectious diseases |
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Title
|
Prevalence and determinants of virological failure, genetic diversity and drug resistance among people living with HIV in a minority area in China: a population-based study. |
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Author
|
Yuan D,Liu M,Jia P,Li Y,Huang Y,Ye L,Api L,Chen M,Yao L,Wang Z,Liu H,Liang S,Yang S |
|
Evidence
|
The most common mutations in NNRTIs were K103N/KN (64.69%), V179D/E (23.47%) and Y181C/YC/I (14.00%), they were M184V/MV/I (36.29%), T215F/FS/TNSY (7.50%) and K219Q (5.92%) in NRTIs, and they were Q58E/QE (4.93%), L10F/LFI (0.39%) and M46L (0.39%) in PIs (Fig. 2).
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HIV Mutation Detail Information