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Mutation Information
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Mutation Site
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Q58E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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PR |
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Relevant Drug
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PIs |
Literature Information
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PubMed PMID
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32411655
|
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Published Year
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2020 |
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Journal
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Frontiers in chemistry |
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Title
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An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site Dissimilarities. |
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Author
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Alves NG,Mata AI,Luís JP,Brito RMM,Simões CJV |
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Evidence
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Major mutations: D30N, V32I, L33F, M46IL, I47VA, G48VM, I50VL, I54VTALM, L76V, V82AFTSL, I84V, N88SD, and L90M;Minor mutations: L10FIVRY, V11IL, K20RIMTV, L23I, L24IFM, M36I, K43T, M46V, G48ASTQL, F53LY, I54ST, Q58E, A71VTIL, G73STCADV, T74PS, V82MC, N83DS, I84AC, I85V, N88TG, and L89VT.
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HIV Mutation Detail Information