|
Mutation Information
|
Mutation Site
|
Q58E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
nelfinavir (NFV);tipranavir (TPV) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
32371875
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Scientific reports |
|
Title
|
HIV-1 molecular epidemiology and drug resistance-associated mutations among treatment-naïve blood donors in China. |
|
Author
|
Zhao J,Lv X,Chang L,Ji H,Harris BJ,Zhang L,Jiang X,Guo F,Hackett J Jr,Yin P,Cloherty GA,Rodgers MA,Wang L |
|
Evidence
|
Most of the PI accessory DRMs were Q58E (3 out of 4) and all the HIV-1 isolates with Q58E mutations in our study were CRF07_BC strains.
|
|
|
HIV Mutation Detail Information