|
Mutation Information
|
Mutation Site
|
Q58E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
PIs |
|
Country
|
Tanzania |
Literature Information
|
PubMed PMID
|
27076106
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults. |
|
Author
|
Hawkins C,Ulenga N,Liu E,Aboud S,Mugusi F,Chalamilla G,Sando D,Aris E,Carpenter D,Fawzi W |
|
Evidence
|
Twenty-five patients had a single non-polymorphic or polymorphic accessory mutation, none of which has been shown to be associated with high levels of phenotypic PI resistance (A71T, n = 4; L10I, n = 12; L10V, n = 6; L33F, n = 2; and Q58E, n = 1).
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HIV Mutation Detail Information