Mutation Information
Mutation Site
|
Q44N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
19014951
|
Published Year
|
2009 |
Journal
|
Journal of molecular biology |
Title
|
Defining the DNA substrate binding sites on HIV-1 integrase. |
Author
|
Dolan J,Chen A,Weber IT,Harrison RW,Leis J |
Evidence
|
In contrast, Q44N, L68E E69P, D229I S230E, and D253N maintained the ability to cleave the HIV-1 substrate, and gained the ability to cleave the ASV substrates to different extents (Figure 3).
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