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Mutation Information
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Mutation Site
|
Q2E |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
L1 |
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Amino acid_Mutation
|
C5562G |
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Genotype/Subtype
|
HPV16 |
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Country
|
India |
Literature Information
|
PubMed PMID
|
19358280
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2009 |
|
Journal
|
International journal of cancer |
|
Title
|
Molecular variants of HPV-16 associated with cervical cancer in Indian population. |
|
Author
|
Pillai MR,Hariharan R,Babu JM,Lakshmi S,Chiplunkar SV,Patkar M,Tongaonkar H,Dinshaw K,Jayshree RS,Reddy BK,Siddiqui M,Roychoudury S,Saha B,Abraham P,Gnanamony M,Peedicayil A,Subhashini J,Ram TS,Dey B,Sharma C,Jain SK,Singh N |
|
Evidence
|
The other frequent variants detected at all the centres were C5562G at the genome level which led to a protein change of Q2E, and ranged from 9 to 19%, C5682T at genome level and H102Y at the protein level and ranged from 8 to 19%, C6163A at genome level and T202N at protein level ranging from 9 to 21%, A6178C at genome level and N207T at protein level ranging from 5 to 16%, A6693C at genome level and T379P at protein level was seen in 8 to 21%, G7058T at genome level and L500F at protein level was seen in 8 to 18%.
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HPV Mutation Detail Information