|
Mutation Information
|
Mutation Site
|
Q219A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
|
Viral Reference
|
K02013.1
|
Literature Information
|
PubMed PMID
|
24415937
|
|
Published Year
|
2014 |
|
Journal
|
PLoS pathogens |
|
Title
|
In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. |
|
Author
|
Henning MS,Dubose BN,Burse MJ,Aiken C,Yamashita M |
|
Evidence
|
We depleted endogenous CPSF6 and infected the cells either with CA mutants that become dependent on cell division (E45A, Q63A/Q67A, A92E, G94D, and Q219A) or those that are impaired for infection but maintain cell cycle independence for infection (P38A, E71A, E128A/R132A and R143A).
|
|
|
HIV Mutation Detail Information