|
Mutation Information
|
Mutation Site
|
Q181R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28325923
|
|
Disease
|
HBV infection
|
|
Published Year
|
2017 |
|
Journal
|
Emerging microbes & infections |
|
Title
|
Clinical features and viral quasispecies characteristics associated with infection by the hepatitis B virus G145R immune escape mutant. |
|
Author
|
Xue Y,Wang MJ,Yang ZT,Yu DM,Han Y,Huang D,Zhang DH,Zhang XX |
|
Evidence
|
Moreover, the frequencies of mutations (L173P, Q181R and A184V) in cytotoxic T lymphocyte epitopes increased before entecavir treatment.
|
|
|
HBV Mutation Detail Information