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Mutation Information
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Mutation Site
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Q151M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
efavirenz (EFV);nevirapine (NPV);lamivudine (LAM);emtricitabine (FTC);abacavir (ABC);zidovudine (AZT);stavudine (D4T);didanosine (DDI);emtricitabine (FTC) |
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Country
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Togo |
Literature Information
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PubMed PMID
|
21663632
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2011 |
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Journal
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Journal of the International AIDS Society |
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Title
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High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo. |
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Author
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Dagnra AY,Vidal N,Mensah A,Patassi A,Aho K,Salou M,Monleau M,Prince-David M,Singo A,Pitche P,Delaporte E,Peeters M |
|
Evidence
|
Among the 46 ARV-resistant patients, 25 also harboured the M184V mutation conferring resistance to 3TC/FTC; among them, eight patients were also resistant to the other NRTI drug in their regimen because of the high number of TAMs (n = 4), or the presence of the Q151M (n = 1) or the K65R (n = 3) mutation. This implied that they were resistant to all three drugs of their ARV regimes.
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HIV Mutation Detail Information