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Mutation Information
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Mutation Site
|
Q14H |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
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Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
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Literature Information
|
PubMed PMID
|
26318249
|
|
Published Year
|
2015 |
|
Journal
|
Virology |
|
Title
|
The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7. |
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Author
|
Togtema M,Jackson R,Richard C,Niccoli S,Zehbe I |
|
Evidence
|
To elucidate the functional effects of this polymorphism, we followed keratinocytes transduced with E-T350G E6 for over 60 passages and compared them to keratinocytes transduced, in parallel, with prototype or Asian-American (Q14H/L83V/H78Y) E6.
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HPV Mutation Detail Information