Mutation Information
Mutation Site
|
Q148R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Relevant Drug
|
INSTIs |
Literature Information
PubMed PMID
|
31965175
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
The Journal of infectious diseases |
Title
|
Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2. |
Author
|
Tzou PL,Descamps D,Rhee SY,Raugi DN,Charpentier C,Taveira N,Smith RA,Soriano V,de Mendoza C,Holmes SP,Gottlieb GS,Shafer RW |
Evidence
|
In PR, 12 nonpolymorphic TSMs occurred in >=11 persons: V33I, K45R, V47A, I50V, I54M, T56V, V62A, A73G, I82F, I84V, F85L, L90M. In RT, 9 nonpolymorphic TSMs occurred in >=10 persons: K40R, A62V, K70R, Y115F, Q151M, M184VI, S215Y. In IN, 11 nonpolymorphic TSMs occurred in >=4 persons: Q91R, E92AQ, T97A, G140S, Y143G, Q148R, A153G, N155H, H156R, R231 5-amino acid insertions.
|
|
|