|
Mutation Information
|
Mutation Site
|
Q148R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
dolutegravir (DTG) |
Literature Information
|
PubMed PMID
|
31370888
|
|
Published Year
|
2019 |
|
Journal
|
Infectious diseases of poverty |
|
Title
|
The urgent need for more potent antiretroviral therapy in low-income countries to achieve UNAIDS 90-90-90 and complete eradication of AIDS by 2030. |
|
Author
|
Ndashimye E,Arts EJ |
|
Evidence
|
Once daily dosage of DTG can be given to patients initiating cART and those failing RAL-based cART as once or twice daily dosage depending on presence of integrase strand transfer inhibitors (INSTIs) mutations more so Q148K/R/H.
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HIV Mutation Detail Information