HIV Mutation Detail Information

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Mutation Information

Mutation Site	Q148R
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Relevant Drug	INSTIs
Country	Turkey

Literature Information

PubMed PMID	27125365
Disease	HIV infection/AIDS
Published Year	2016
Journal	HIV clinical trials
Title	Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients.
Author	Sayan M,Gündüz A,Ersöz G,İnan A,Deveci A,Özgür G,Sargın F,Karagöz G,İnci A,İnan D,Ülçay A,Karaoğlan I,Kaya S,Kutlu SS,Süer K,Çağatay A,Akalın H
Evidence	However, ARV-experienced patients had major resistance mutations associated with raltegravir and elvitegravir;the following results were generated:F121Y, Y143R, Q148R and E157Q (6/91 - 6.6%).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation