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Mutation Information
|
Mutation Site
|
Q148K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
32125378
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Impact of genotypic diversity on selection of subtype-specific drug resistance profiles during raltegravir-based therapy in individuals infected with B and BF recombinant HIV-1 strains. |
|
Author
|
Sánchez D,Arazi Caillaud S,Zapiola I,Fernandez Giuliano S,Bologna R,Mangano A,Aulicino PC |
|
Evidence
|
INI DRMs differed between B and F IN subtypes, with Q148K/R/H, G140S and E138K/A being more prevalent in subtype B (63% versus 0%, P = 0.0021;50% versus 0%, P = 0.0096;and 50% versus 0%, P = 0.0096, respectively).
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HIV Mutation Detail Information