|
Mutation Information
|
Mutation Site
|
Q129R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Amino acid_Mutation
|
T540C |
Literature Information
|
PubMed PMID
|
9303514
|
|
Clinical information
|
Yes
|
|
Disease
|
Fulminant hepatitis B;
Acute hepatitis B
|
|
Published Year
|
1997 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis. |
|
Author
|
Hsu HY,Chang MH,Ni YH,Lin HH,Wang SM,Chen DS |
|
Evidence
|
An S mutant (residue 129, Gln to Arg) found in one mother-infant pair suggested a direct maternal-infant transmission, resulting in immunoprophylaxis failure.
|
|
|
HBV Mutation Detail Information