HBV Mutation Detail Information

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Mutation Information
Mutation Site Q129R
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype A
Country Botswana
Literature Information
PubMed PMID 30382563
Disease HBV-HIV coinfection
Published Year 2019
Journal Virus genes
Title Molecular characterization of hepatitis B virus in blood donors in Botswana.
Author Choga WT,Anderson M,Zumbika E,Moyo S,Mbangiwa T,Phinius BB,Melamu P,Kayembe MK,Kasvosve I,Sebunya TK,Blackard JT,Essex M,Musonda RM,Gaseitsiwe S
Evidence Twelve mutations including diagnostic escape mutations (sY100C, sR122K, sT123A, sC124R, sM133T), vaccine escape mutations (sT126N, sQ129R, sM133L, sF134V) and immunoglobulin therapy failure (sG119R, sG130N, sT140S) were exclusive to isolates obtained from HBV/HIV patients versus n = 4 including sP120L, sG130R, sY134H, and sD144A) (Fig 4) obtained from some isolates from blood donors.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation