HIV Mutation Detail Information

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Mutation Information

Mutation Site	Q125H
Mutation Type	Amino acid level
Gene/Protein/Region Type	Nef
Combined Mutation	nef.Q125H+nef.Y120F
Country	Japan

Literature Information

PubMed PMID	33173092
Disease	HIV infection/AIDS
Published Year	2020
Journal	Scientific reports
Title	Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals.
Author	Toyoda M,Kamori D,Tan TS,Goebuchi K,Ohashi J,Carlson J,Kawana-Tachikawa A,Gatanaga H,Oka S,Pizzato M,Ueno T
Evidence	By breaking down the specific HLA allele-associated mutations, we found that a number of the HLA-B*51:01-associated Y120F and Q125H mutations were most significantly associated with a reduced plasma viral load.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation